EIF3CL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EIF3CL mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF3CL-associated genes across cancer lineages are HTN1, ODF4, and CCER1. Each is linked with EIF3CL in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3CL-to-partner and partner-to-EIF3CL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3CL→partner) and Y-score (partner→EIF3CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYHTN1 →+0.050+5.000<.001.00531
KIDNEYODF4 →+0.030+5.000<.001.00531
KIDNEYCCER1 →+0.006+5.000<.001.00531
KIDNEYKRTAP9-9 →+0.020+5.000<.001.00531
KIDNEYDEFA3 →+0.170+5.000<.001.00531
PANCREASLRRC10 →+0.006+4.011<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

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