Across TCGA patient cohorts, EIF3C mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF3C-associated genes across cancer lineages are CICP28, MIR378E, and MIR4767. Each is linked with EIF3C in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3C-to-partner and partner-to-EIF3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3C→partner) and Y-score (partner→EIF3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CICP28 →	+0.037	+3.936	.001	.005	3	1
UCEC	MIR378E →	+0.736	+4.868	<.001	.004	3	1
UCEC	MIR4767 →	+1.456	+3.879	<.001	.008	3	1
UCEC	RN7SL140P →	+0.199	+4.997	<.001	.003	3	1
UCEC	RNU6-1292P →	+0.713	+4.868	<.001	.004	3	1
UCEC	RNU6-466P →	+0.714	+3.661	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

EIF3C survival (RNA) · tumor vs normal (RNA) · all EIF3C data types