EIF3A

Across TCGA patient cohorts, EIF3A protein abundance is significantly associated with the RNA expression of many other genes, with 15,743 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF3A-associated genes across cancer lineages are LINC00702, FGF1, and DACT3. Each is linked with EIF3A in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF3A-to-partner and partner-to-EIF3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF3A versus LINC00702 in HNSC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3A→partner) and Y-score (partner→EIF3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC00702 →	-0.726	-0.129	<.001	<.001	3	8
OV	FGF1 →	-1.188	-0.177	<.001	<.001	3	7
OV	DACT3 →	-0.602	-0.154	<.001	<.001	3	7
CCRCC	PTH1R →	-0.989	-0.129	.008	.003	3	7
COAD	LMOD1 →	-1.331	-0.180	<.001	<.001	3	7
GBM	SEPTIN4 →	-0.715	-0.129	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,743 associations by consensus.

EIF3A vs LINC00702 — HNSC

Explore this scatter interactively →