EIF2S2P4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EIF2S2P4 protein abundance is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EIF2S2P4-associated genes across cancer lineages are TRAJ33, ATP6V0E1P3, and DOP1B. Each is linked with EIF2S2P4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF2S2P4-to-partner and partner-to-EIF2S2P4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2S2P4 versus TRAJ33 in BRCA, with a Pearson correlation of -0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S2P4→partner) and Y-score (partner→EIF2S2P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATRAJ33 →-2.445-0.862<.001.00931
BRCAATP6V0E1P3 →-0.675-0.862.004.00931
BRCADOP1B →+1.590+0.589.005.00921
BRCADUSP6 →+2.473+0.589<.001.00911
BRCAMUCL1 →+5.183+0.589<.001.00911
BRCAGRK5 →+1.123+0.590.004.00911
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

EIF2S2P4 vs TRAJ33 — BRCA

Per-sample scatter of EIF2S2P4 vs TRAJ33 in BRCA (Pearson r = -0.87).

Explore this scatter interactively →

Exploration