EIF2S2P4

Across TCGA pan-cancer cohorts, EIF2S2P4 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated EIF2S2P4 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher EIF2S2P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF2S2P4 expression acts as an unfavorable survival marker, although some lineages such as READ and UCS show a favorable association.

PAAD, READ, and UVM are the cancer types where EIF2S2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Median	All	0.358	0.602	<.001	77	view →
READ	DFS	Tertile	II,III,IV	0.936	0.660	<.001	74	view →
UVM	DFS	Tertile	III,IV	0.294	0.775	.001	51	view →
KIRP	OS	Quartile	All	0.881	0.979	.001	51	view →
ACC	OS	Quartile	All	0.399	0.736	.001	49	view →
BRCA	DFS	Median	All	0.871	0.927	<.001	49	view →
LIHC	OS	Quartile	All	0.498	0.765	<.001	43	view →
MESO	DFS	Median	III,IV	0.285	0.457	.010	40	view →
KICH	OS	Tertile	II,III,IV	0.556	1.000	.010	33	view →
UCS	DFS	Tertile	IV	0.981	0.237	.024	24	view →
LGG	OS	Median	All	0.339	0.543	<.001	22	view →
LUAD	OS	Tertile	All	0.316	0.530	.005	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

EIF2S2P4–PAAD (OS)

Open the PAAD breakdown →