EIF2S2

Across TCGA patient cohorts, EIF2S2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,773 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EIF2S2-associated genes across cancer lineages are ABCA8, LMOD1, and JAM3. Each is linked with EIF2S2 in more than 8 cancer types. Because this analysis shows association rather than direction, both EIF2S2-to-partner and partner-to-EIF2S2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2S2 versus ABCA8 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S2→partner) and Y-score (partner→EIF2S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABCA8 →	-1.225	-0.186	<.001	<.001	3	9
OV	LMOD1 →	-1.150	-0.282	<.001	<.001	3	8
OV	JAM3 →	-0.807	-0.280	.001	<.001	3	8
GBM	PHYHIP →	-1.370	-0.249	<.001	<.001	3	8
HNSC	SYNPO2 →	-1.167	-0.168	.002	<.001	3	8
OV	MAGI2-AS3 →	-0.737	-0.254	.004	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,773 associations by consensus.

EIF2S2 vs ABCA8 — UCEC

Explore this scatter interactively →