EIF2S1

Across TCGA patient cohorts, EIF2S1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,812 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF2S1-associated proteins across cancer lineages are MTHFD1, SUPT16H, and NAA35. Each is linked with EIF2S1 in more than 8 cancer types. Because this analysis shows association rather than direction, both EIF2S1-to-partner and partner-to-EIF2S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2S1 versus MTHFD1 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2S1→partner) and Y-score (partner→EIF2S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MTHFD1 →	+0.471	+0.555	<.001	<.001	3	9
GBM	SUPT16H →	+0.435	+0.399	<.001	<.001	3	8
OV	NAA35 →	+0.223	+0.339	<.001	<.001	3	8
GBM	SSRP1 →	+0.437	+0.378	<.001	<.001	3	7
OV	UBR7 →	+0.397	+0.416	.001	.002	2	8
LSCC	WDHD1 →	+0.636	+0.465	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,812 associations by consensus.

EIF2S1 vs MTHFD1 — OV

Explore this scatter interactively →