EIF2AK4

Across TCGA patient cohorts, EIF2AK4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,399 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF2AK4-associated genes across cancer lineages are H3P38, SRP14, and CHADL. Each is linked with EIF2AK4 in more than 3 cancer types. Because this analysis shows association rather than direction, both EIF2AK4-to-partner and partner-to-EIF2AK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2AK4 versus H3P38 in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2AK4→partner) and Y-score (partner→EIF2AK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	H3P38 →	+0.705	+0.252	<.001	<.001	3	4
OV	SRP14 →	+0.761	+0.261	<.001	<.001	3	4
GBM	CHADL →	-0.906	-0.198	<.001	<.001	3	3
CCRCC	ASPA →	-1.231	-0.189	<.001	<.001	3	3
GBM	HLF →	-0.985	-0.233	.001	.008	3	3
GBM	TGFBI →	+1.492	+0.237	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,399 associations by consensus.

EIF2AK4 vs H3P38 — LSCC

Explore this scatter interactively →