EIF2AK3

Across TCGA patient cohorts, EIF2AK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,614 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF2AK3-associated proteins across cancer lineages are NUCB2, SERPINI1, and KDM3A. Each is linked with EIF2AK3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EIF2AK3-to-partner and partner-to-EIF2AK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2AK3 versus NUCB2 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2AK3→partner) and Y-score (partner→EIF2AK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUCB2 →	+0.614	+0.721	<.001	<.001	3	4
HNSC	SERPINI1 →	+0.720	+0.410	<.001	.001	3	4
LSCC	KDM3A →	+0.378	+0.311	.003	.001	3	4
OV	UBA5 →	+0.654	+0.384	.004	.001	3	4
HNSC	SPAST →	+0.446	+0.540	<.001	<.001	3	4
UCEC	TMEM263 →	+0.282	+0.492	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,614 associations by consensus.

EIF2AK3 vs NUCB2 — BRCA

Explore this scatter interactively →