EIF2AK3

Across TCGA patient cohorts, EIF2AK3 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,858 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EIF2AK3-associated proteins across cancer lineages are MOGS, C11orf68, and WASHC1. Each is linked with EIF2AK3 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF2AK3-to-partner and partner-to-EIF2AK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF2AK3 versus MOGS in UCEC, with a Pearson correlation of 0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF2AK3→partner) and Y-score (partner→EIF2AK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MOGS →	+0.591	+0.462	<.001	.001	3	7
PDAC	C11orf68 →	-0.344	-0.378	<.001	<.001	3	6
PDAC	WASHC1 →	-0.389	-0.603	<.001	<.001	3	6
PDAC	SEPTIN2 →	-0.327	-0.448	<.001	<.001	3	6
BRCA	ATP13A3 →	+0.421	+0.552	.001	<.001	3	5
PDAC	CAPZA2 →	-0.374	-0.364	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,858 associations by consensus.

EIF2AK3 vs MOGS — UCEC

Explore this scatter interactively →