EIF1P4

Across TCGA pan-cancer cohorts, EIF1P4 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of EIF1P4’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where EIF1P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EIF1P4 is over-expressed in tumor, although a few such as PRAD and HNSC show the opposite, repressed pattern.

LUSC, COAD, and ESCA are the cancer types where EIF1P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF1P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	+0.425	<.001	6	view →
COAD	All	II,III,IV	+0.294	.002	5	view →
ESCA	All	II,III,IV	+0.835	.004	2	view →
CHOL	Male	All	+0.655	.019	2	view →
LUAD	All	III,IV	+0.311	.017	2	view →
PRAD	All	All	−0.170	.022	2	view →
HNSC	Female	IV	−0.263	.048	1	view →
KIRC	Female	III,IV	−0.069	.037	1	view →
KIRP	All	III,IV	−0.042	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

EIF1P4–LUSC

Open the LUSC breakdown →