EIF1B-AS1

Across TCGA pan-cancer cohorts, EIF1B-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated EIF1B-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher EIF1B-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EIF1B-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and KIRC show a favorable association.

UVM, KIRC, and SKCM are the cancer types where EIF1B-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.862	0.397	<.001	114	view →
KIRC	DFS	Median	All	0.729	0.537	<.001	74	view →
SKCM	OS	Median	All	0.409	0.259	<.001	60	view →
BRCA	OS	Tertile	All	0.979	0.942	<.001	55	view →
ACC	OS	Tertile	II,III,IV	1.000	0.736	.001	50	view →
LIHC	DFS	Tertile	All	0.156	0.423	.003	41	view →
READ	OS	Median	All	0.921	0.725	.005	35	view →
MESO	OS	Tertile	All	0.507	0.268	.003	30	view →
SARC	OS	Median	All	0.621	0.359	<.001	19	view →
THYM	DFS	Median	III,IV	1.000	0.399	.004	16	view →
UCS	DFS	Median	IV	0.909	0.416	.008	16	view →
ESCA	DFS	Median	IV	0.213	0.626	.026	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

EIF1B-AS1–UVM (OS)

Open the UVM breakdown →