EIF1B-AS1

Across TCGA pan-cancer cohorts, EIF1B-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of EIF1B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where EIF1B-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types EIF1B-AS1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRC are the cancer types where EIF1B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF1B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	IV	−0.660	<.001	11	view →
KICH	Female	II,III,IV	−0.760	<.001	10	view →
KIRC	All	II,III,IV	−0.234	<.001	10	view →
LUSC	All	II,III,IV	−0.196	<.001	7	view →
UCEC	All	II,III,IV	−0.651	<.001	6	view →
BRCA	All	III,IV	−0.476	<.001	6	view →
LIHC	Male	All	+0.231	<.001	5	view →
LUAD	Female	II,III,IV	−0.260	<.001	4	view →
KIRP	Male	III,IV	−0.257	.011	3	view →
PRAD	All	All	−0.308	<.001	2	view →
READ	All	III,IV	−0.219	.047	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

EIF1B-AS1–THCA

Open the THCA breakdown →