EID3

Across TCGA patient cohorts, EID3 mutation is significantly associated with the RNA expression of many other genes, with 2,295 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EID3-associated genes across cancer lineages are PGBD4P2, RN7SL248P, and MIR4695. Each is linked with EID3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EID3-to-partner and partner-to-EID3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PGBD4P2 grouped by EID3-low versus EID3-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EID3→partner) and Y-score (partner→EID3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	2
UCEC	RN7SL248P →	+0.078	+3.552	<.001	<.001	3	2
LUAD	MIR4695 →	+0.348	+7.930	<.001	.008	3	2
SKCM	ZNF736P7Y →	+0.054	+7.816	<.001	.008	3	2
UCEC	SNORD3B-2 →	+0.482	+3.332	.007	<.001	3	2
UCEC	AQP7P3 →	+0.024	+2.919	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,295 associations by consensus.

PGBD4P2 by EID3 expression — READ

Explore this box plot interactively →