EID2B

Across TCGA patient cohorts, EID2B mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EID2B-associated genes across cancer lineages are MIR449B, MIR6859-2, and CTBP2P3. Each is linked with EID2B in more than 1 cancer types. Because this analysis shows association rather than direction, both EID2B-to-partner and partner-to-EID2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR449B grouped by EID2B-low versus EID2B-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EID2B→partner) and Y-score (partner→EID2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR449B →	+0.323	+7.954	<.001	.008	3	1
UCEC	MIR6859-2 →	+0.728	+3.690	<.001	.009	3	1
UCEC	CTBP2P3 →	+0.070	+4.038	.001	.004	3	1
LGG	MTND6P1 →	+0.104	+7.977	<.001	.007	3	1
LGG	RNU6-599P →	+0.348	+7.977	<.001	.007	3	1
LGG	RNU4ATAC4P →	+0.264	+7.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

MIR449B by EID2B expression — HNSC

Explore this box plot interactively →