EID2B

Across TCGA pan-cancer cohorts, EID2B RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of EID2B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where EID2B RNA is repressed in tumor relative to normal tissue. In most cancer types EID2B is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, KIRP, and LIHC are the cancer types where EID2B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EID2B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.326	<.001	10	view →
KIRP	All	II,III,IV	+0.792	<.001	9	view →
LIHC	All	II,III,IV	+0.605	<.001	9	view →
HNSC	All	II,III,IV	+0.326	.001	7	view →
LUAD	Female	III,IV	−0.681	<.001	6	view →
CHOL	Female	All	+1.563	<.001	5	view →
UCEC	All	All	−1.101	<.001	4	view →
BRCA	Female	All	−0.343	<.001	4	view →
LUSC	All	III,IV	−0.831	.005	3	view →
LUAD	All	IV	+1.225	.005	2	view →
COAD	Male	II,III,IV	−0.338	.026	2	view →
PRAD	All	All	−0.305	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

EID2B–KICH

Open the KICH breakdown →