EHHADH

Across TCGA patient cohorts, EHHADH mutation is significantly associated with the RNA expression of many other genes, with 1,617 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EHHADH-associated genes across cancer lineages are MIR563, MIR185, and DYNLL1P5. Each is linked with EHHADH in more than 2 cancer types. Because this analysis shows association rather than direction, both EHHADH-to-partner and partner-to-EHHADH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR563 grouped by EHHADH-low versus EHHADH-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EHHADH→partner) and Y-score (partner→EHHADH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR563 →	+0.497	+4.245	.005	.008	3	3
SKCM	MIR185 →	+0.208	+2.563	<.001	.002	3	3
BLCA	DYNLL1P5 →	+0.187	+3.971	.001	.005	3	3
CESC	MIR7976 →	+0.524	+3.269	.001	.008	3	3
UCEC	RNU6-879P →	+0.289	+1.793	.003	.001	3	3
PRAD	RN7SKP85 →	+0.156	+7.117	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,617 associations by consensus.

MIR563 by EHHADH expression — HNSC

Explore this box plot interactively →