Across TCGA pan-cancer cohorts, EHHADH-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated EHHADH-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher EHHADH-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EHHADH-AS1 expression acts as an unfavorable survival marker, although some lineages such as LIHC and SKCM show a favorable association.

KICH, COAD, and BRCA are the cancer types where EHHADH-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.025	0.904	<.001	108	view →
COAD	DFS	Tertile	All	0.407	0.803	<.001	45	view →
BRCA	OS	Tertile	IV	0.420	0.827	.008	36	view →
UCEC	OS	Tertile	All	0.765	0.884	.003	36	view →
THYM	DFS	Tertile	II,III,IV	0.123	0.851	<.001	27	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
UVM	DFS	Tertile	All	0.285	0.769	.010	24	view →
GBM	OS	Tertile	All	0.245	0.438	.002	18	view →
READ	DFS	Tertile	All	0.154	0.565	.026	18	view →
LIHC	DFS	Tertile	III,IV	0.768	0.218	.045	12	view →
LUSC	DFS	Tertile	II,III,IV	0.476	0.767	.046	3	view →
SKCM	DFS	Quartile	II,III,IV	0.364	0.253	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration

Same gene, other analysis: EHHADH-AS1 tumor-vs-normal RNA expression · all EHHADH-AS1 data types