Across TCGA pan-cancer cohorts, EHHADH-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of EHHADH-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where EHHADH-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EHHADH-AS1 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.

HNSC, UCEC, and LIHC are the cancer types where EHHADH-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EHHADH-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.030	.040	5	view →
UCEC	All	IV	+0.090	.046	2	view →
LIHC	Female	All	−0.019	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: EHHADH-AS1 RNA expression & survival · all EHHADH-AS1 data types