EGR1

Across TCGA patient cohorts, EGR1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,258 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EGR1-associated genes across cancer lineages are EFCAB11, PELATON, and SH3RF3-AS1. Each is linked with EGR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EGR1-to-partner and partner-to-EGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGR1 versus EFCAB11 in LUAD, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGR1→partner) and Y-score (partner→EGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	EFCAB11 →	-0.732	-0.652	<.001	.004	3	2
PDAC	PELATON →	+0.703	+1.644	.002	.002	3	2
UCEC	SH3RF3-AS1 →	+0.704	+0.941	.001	<.001	3	2
PDAC	FCGR3B →	+2.262	+1.847	<.001	.001	3	2
PDAC	CXCR1 →	+1.484	+1.900	.006	.003	3	2
PDAC	CXCL5 →	+3.567	+1.577	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,258 associations by consensus.

EGR1 vs EFCAB11 — LUAD

Explore this scatter interactively →