EGOT

Across TCGA patient cohorts, EGOT RNA expression is significantly associated with the protein abundance of many other proteins, with 17,945 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EGOT-associated proteins across cancer lineages are MTHFD2, NFKB1, and RPL3. Each is linked with EGOT in more than 4 cancer types. Because this analysis shows association rather than direction, both EGOT-to-partner and partner-to-EGOT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGOT versus MTHFD2 in LUAD, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGOT→partner) and Y-score (partner→EGOT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTHFD2 →	-0.579	-0.707	<.001	<.001	3	5
BRCA	NFKB1 →	+0.279	+1.326	.001	<.001	3	5
LUAD	RPL3 →	-0.418	-0.674	<.001	<.001	3	5
CCRCC	SLC7A5 →	-1.272	-1.183	<.001	<.001	3	5
HNSC	EEF1G →	-0.272	-0.609	<.001	.002	3	5
GBM	JPT1 →	-0.432	-0.537	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,945 associations by consensus.

EGOT vs MTHFD2 — LUAD

Explore this scatter interactively →