EGLN3P1

Across TCGA pan-cancer cohorts, EGLN3P1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated EGLN3P1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher EGLN3P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EGLN3P1 expression acts as an unfavorable survival marker, although some lineages such as STAD and HNSC show a favorable association.

STAD, HNSC, and DLBC are the cancer types where EGLN3P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	III,IV	0.746	0.546	.005	33	view →
HNSC	OS	Tertile	IV	0.503	0.357	.004	32	view →
DLBC	DFS	Tertile	All	0.468	0.940	.006	27	view →
THCA	DFS	Median	IV	0.444	0.801	.006	26	view →
ACC	DFS	Tertile	II,III,IV	0.788	0.298	.033	21	view →
LUAD	OS	Quartile	III,IV	0.863	0.611	.008	17	view →
LUSC	DFS	Quartile	III,IV	0.868	0.530	.010	12	view →
SKCM	OS	Quartile	All	0.250	0.393	.014	9	view →
ESCA	OS	Tertile	III,IV	0.638	0.301	.019	5	view →
CHOL	OS	Quartile	All	0.267	0.683	.038	3	view →
READ	DFS	Quartile	III,IV	0.977	0.379	.027	3	view →
TGCT	DFS	Tertile	All	0.913	0.787	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

EGLN3P1–STAD (OS)

Open the STAD breakdown →