EGLN3

Across TCGA cell cohorts, EGLN3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EGLN3-associated genes across cancer lineages are CFC1, GPR26, and KLHL40. Each is linked with EGLN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EGLN3-to-partner and partner-to-EGLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFC1 grouped by EGLN3-low versus EGLN3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGLN3→partner) and Y-score (partner→EGLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CFC1 →	+0.882	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	GPR26 →	+0.026	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	KLHL40 →	+0.013	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	C1orf87 →	+0.021	+4.867	.008	.009	3	1
BLOOD_Lymphoma	MRGPRG →	+0.056	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	C14orf180 →	+0.022	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

CFC1 by EGLN3 expression — BLOOD_Lymphoma

Explore this box plot interactively →