EGFLAM-AS4

Across TCGA patient cohorts, EGFLAM-AS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,044 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EGFLAM-AS4-associated GO terms across cancer lineages are Regulation of protein serine/threonine kinase activity, Negative regulation of transferase activity, and Regulation of RNA splicing. Each is linked with EGFLAM-AS4 in more than 9 cancer types. Because this analysis shows association rather than direction, both EGFLAM-AS4-to-partner and partner-to-EGFLAM-AS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein serine/threonine kinase activity grouped by EGFLAM-AS4-low versus EGFLAM-AS4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFLAM-AS4→partner) and Y-score (partner→EGFLAM-AS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein serine/threonine kinase activity →	+0.043	+0.046	<.001	<.001	3	10
STAD	Negative regulation of transferase activity →	+0.048	+0.047	<.001	<.001	3	9
STAD	Regulation of RNA splicing →	+0.056	+0.050	<.001	<.001	3	9
STAD	Negative regulation of apoptotic signaling pathway →	+0.052	+0.055	<.001	<.001	3	9
STAD	Neural tube development →	+0.048	+0.055	<.001	<.001	3	9
STAD	Regulation of protein ubiquitination →	+0.050	+0.049	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,044 associations by consensus.

Regulation of protein serine/threonine kinase activity by EGFLAM-AS4 expression — STAD

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