EGFLAM-AS4

Across TCGA pan-cancer cohorts, EGFLAM-AS4 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated EGFLAM-AS4 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher EGFLAM-AS4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EGFLAM-AS4 expression acts as an unfavorable survival marker, although some lineages such as LIHC and UCS show a favorable association.

CHOL, SKCM, and KIRC are the cancer types where EGFLAM-AS4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	II,III,IV	0.016	0.406	<.001	72	view →
SKCM	DFS	Tertile	All	0.427	0.694	<.001	66	view →
KIRC	DFS	Tertile	All	0.468	0.656	.001	48	view →
BRCA	OS	Tertile	All	0.357	0.602	.009	24	view →
THYM	OS	Tertile	III,IV	0.615	1.000	.019	21	view →
LIHC	DFS	Tertile	II,III,IV	0.706	0.401	.024	21	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
UCS	OS	Tertile	IV	0.844	0.250	.016	18	view →
STAD	DFS	Quartile	IV	0.083	0.366	.004	14	view →
BLCA	OS	Tertile	All	0.835	0.641	.042	6	view →
TGCT	DFS	Tertile	All	0.543	0.786	.037	6	view →
PAAD	OS	Tertile	All	0.621	0.355	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

EGFLAM-AS4–CHOL (DFS)

Open the CHOL breakdown →