EGFLAM-AS1

Across TCGA pan-cancer cohorts, EGFLAM-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated EGFLAM-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher EGFLAM-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EGFLAM-AS1 expression acts as an unfavorable survival marker, although some lineages such as TGCT and PCPG show a favorable association.

UVM, ACC, and MESO are the cancer types where EGFLAM-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.136	0.919	<.001	90	view →
ACC	DFS	Tertile	All	0.039	0.636	<.001	81	view →
MESO	OS	Tertile	II,III,IV	0.217	0.582	.010	51	view →
BRCA	DFS	Tertile	II,III,IV	0.451	0.525	.022	21	view →
KIRC	DFS	Tertile	IV	0.259	0.617	.011	18	view →
THCA	OS	Tertile	II,III,IV	0.894	0.989	.004	18	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	18	view →
LUSC	DFS	Tertile	All	0.430	0.658	.004	18	view →
GBM	DFS	Tertile	All	0.099	0.257	<.001	9	view →
ESCA	DFS	Tertile	All	0.419	0.795	.041	9	view →
HNSC	OS	Tertile	All	0.673	0.782	.029	6	view →
TGCT	DFS	Median	All	0.907	0.759	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

EGFLAM-AS1–UVM (OS)

Open the UVM breakdown →