EGFLAM-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, EGFLAM-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of EGFLAM-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where EGFLAM-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EGFLAM-AS1 is over-expressed in tumor.

HNSC, LUAD, and LUSC are the cancer types where EGFLAM-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EGFLAM-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCMaleAll+0.094.0391view →
LUADAllAll+0.061.0321view →
LUSCAllAll+0.039.0441view →
KIRCAllAll+0.014.0431view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

EGFLAM-AS1–HNSC

Tumor-vs-normal expression box plot for EGFLAM-AS1 RNA in HNSC.

Open the HNSC breakdown →

Exploration