EGFL8

Across TCGA patient cohorts, EGFL8 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,822 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EGFL8-associated proteins across cancer lineages are CAVIN1_T248, CAVIN2, and CUL4B. Each is linked with EGFL8 in more than 1 cancer types. Because this analysis shows association rather than direction, both EGFL8-to-partner and partner-to-EGFL8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGFL8 versus CAVIN1_T248 in LUAD, with a Pearson correlation of 0.85.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFL8→partner) and Y-score (partner→EGFL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CAVIN1_T248 →	+1.163	+0.904	.001	<.001	3	2
LSCC	CAVIN2 →	+0.583	+0.658	<.001	<.001	3	2
LUAD	CUL4B →	-0.486	-0.973	.001	.002	3	2
LUAD	SERPINA5 →	+0.766	+1.112	.002	.002	3	2
LSCC	LMOD1_S119 →	+1.820	+0.958	<.001	<.001	3	2
LSCC	UPF3B_S310 →	-0.616	-0.903	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,822 associations by consensus.

EGFL8 vs CAVIN1_T248 — LUAD

Explore this scatter interactively →