EGF

Across TCGA patient cohorts, EGF RNA expression is significantly associated with the protein abundance of many other proteins, with 16,130 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EGF-associated proteins across cancer lineages are CRAT, HSD17B8, and ANK3_S959. Each is linked with EGF in more than 3 cancer types. Because this analysis shows association rather than direction, both EGF-to-partner and partner-to-EGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EGF versus CRAT in HNSC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EGF→partner) and Y-score (partner→EGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CRAT →	+0.708	+0.866	<.001	<.001	3	4
HNSC	HSD17B8 →	+0.430	+1.119	.001	<.001	3	4
LUAD	ANK3_S959 →	+0.755	+1.084	<.001	<.001	3	4
LSCC	MAP1A_S1762 →	+1.356	+1.541	.002	.004	3	4
BRCA	NFIC →	+0.390	+1.258	<.001	<.001	3	4
GBM	VWA5A →	+0.545	+0.819	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,130 associations by consensus.

EGF vs CRAT — HNSC

Explore this scatter interactively →