EFS

Across TCGA pan-cancer cohorts, EFS mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EFS data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher EFS mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated EFS expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, HNSC, and UCEC are the cancer types where EFS mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.893	0.289	.003	14	view →
HNSC	DFS	Quartile	IV	0.571	0.918	.019	10	view →
UCEC	OS	Median	II,III,IV	0.638	1.000	.014	4	view →
GBM	OS	Quartile	All	0.400	0.733	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EFS–LUAD (OS)

Open the LUAD breakdown →