Across TCGA cell cohorts, EFNA5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EFNA5-associated genes across cancer lineages are STATH, GK2, and OR4E1. Each is linked with EFNA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFNA5-to-partner and partner-to-EFNA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA5→partner) and Y-score (partner→EFNA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	STATH →	+0.420	+4.643	<.001	.003	3	1
CNS	GK2 →	+0.009	+4.754	<.001	.005	3	1
CNS	OR4E1 →	+0.061	+4.321	<.001	.009	3	1
CNS	PRAMEF18 →	+0.019	+5.285	<.001	<.001	3	1
LUNG_NSCLC_LUAD	MAGEB4 →	+0.006	+5.662	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

EFNA5 survival (RNA) · tumor vs normal (RNA) · all EFNA5 data types