EFNA4

Across TCGA cell cohorts, EFNA4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFNA4-associated genes across cancer lineages are MSGN1, CFAP47, and TRARG1. Each is linked with EFNA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFNA4-to-partner and partner-to-EFNA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by EFNA4-low versus EFNA4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA4→partner) and Y-score (partner→EFNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	CFAP47 →	+0.212	+3.453	.004	.009	3	1
LARGE_INTESTINE	TRARG1 →	+0.022	+3.345	<.001	.007	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.103	+3.453	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MSGN1 by EFNA4 expression — LARGE_INTESTINE

Explore this box plot interactively →