EFNA2

Across TCGA patient cohorts, EFNA2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,401 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFNA2-associated genes across cancer lineages are LMOD1, POLE2, and ERH. Each is linked with EFNA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both EFNA2-to-partner and partner-to-EFNA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFNA2 versus LMOD1 in COAD, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFNA2→partner) and Y-score (partner→EFNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LMOD1 →	-1.443	-0.252	<.001	<.001	3	8
LSCC	POLE2 →	+0.708	+0.192	<.001	<.001	3	7
HNSC	ERH →	+0.978	+0.149	.003	.004	3	7
HNSC	VRK1 →	+1.182	+0.188	<.001	<.001	3	7
HNSC	LMNB1 →	+1.056	+0.212	.002	<.001	3	7
BRCA	NCAPH →	+0.817	+0.183	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,401 associations by consensus.

EFNA2 vs LMOD1 — COAD

Explore this scatter interactively →