EFL1

Across TCGA patient cohorts, EFL1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,800 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFL1-associated genes across cancer lineages are SEC11A, RAMAC, and MESD. Each is linked with EFL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EFL1-to-partner and partner-to-EFL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFL1 versus SEC11A in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFL1→partner) and Y-score (partner→EFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEC11A →	+0.694	+0.339	<.001	<.001	3	7
UCEC	RAMAC →	+0.471	+0.193	<.001	<.001	3	6
OV	MESD →	+0.489	+0.241	.001	.001	3	5
COAD	ICE2 →	+0.385	+0.209	<.001	<.001	3	5
LSCC	DUT →	+0.503	+0.245	.001	.001	3	5
HNSC	NDUFAF1 →	+0.481	+0.248	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,800 associations by consensus.

EFL1 vs SEC11A — OV

Explore this scatter interactively →