EFL1

Across TCGA cell cohorts, EFL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,478 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EFL1-associated GO terms across cancer lineages are Regulation of heterochromatin organization, Termination of RNA polymerase II transcription, and RNA import into nucleus. Each is linked with EFL1 in more than 9 cancer types. Because this analysis shows association rather than direction, both EFL1-to-partner and partner-to-EFL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heterochromatin organization grouped by EFL1-low versus EFL1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFL1→partner) and Y-score (partner→EFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of heterochromatin organization →	+0.080	+0.817	<.001	<.001	3	10
LUNG_SCLC	Termination of RNA polymerase II transcription →	+0.129	+0.576	<.001	.002	3	10
OESOPHAGUS	RNA import into nucleus →	+0.165	+0.739	<.001	<.001	3	10
BLOOD_Leukemia	Centrosome cycle →	+0.050	+0.555	<.001	<.001	3	10
KIDNEY	Positive regulation of chromosome organization →	+0.066	+0.902	.005	.004	3	9
OVARY	Regulation of cell cycle checkpoint →	+0.111	+0.794	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,478 associations by consensus.

Regulation of heterochromatin organization by EFL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →