EFHC1

Across TCGA patient cohorts, EFHC1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,794 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EFHC1-associated genes across cancer lineages are SPEF1, TSNAXIP1, and CCDC113. Each is linked with EFHC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFHC1-to-partner and partner-to-EFHC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFHC1 versus SPEF1 in UCEC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFHC1→partner) and Y-score (partner→EFHC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPEF1 →	+1.825	+0.509	<.001	<.001	3	4
UCEC	TSNAXIP1 →	+1.433	+0.558	<.001	<.001	3	4
UCEC	CCDC113 →	+1.357	+0.697	<.001	<.001	3	4
UCEC	CFAP69 →	+0.939	+0.945	<.001	<.001	3	4
UCEC	NME5 →	+1.044	+0.576	<.001	<.001	3	4
UCEC	CFAP94 →	+1.361	+0.728	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,794 associations by consensus.

EFHC1 vs SPEF1 — UCEC

Explore this scatter interactively →