EFEMP1

Across TCGA patient cohorts, EFEMP1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,736 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EFEMP1-associated genes across cancer lineages are MGP, LTBP2, and COL8A1. Each is linked with EFEMP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both EFEMP1-to-partner and partner-to-EFEMP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFEMP1 versus MGP in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFEMP1→partner) and Y-score (partner→EFEMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MGP →	+1.543	+0.455	.001	.001	3	10
BRCA	LTBP2 →	+1.075	+0.656	<.001	<.001	3	10
OV	COL8A1 →	+1.744	+0.912	<.001	<.001	3	10
OV	ABCA6 →	+0.971	+0.824	<.001	<.001	3	10
BRCA	MSRB3 →	+1.133	+0.576	<.001	<.001	3	10
HNSC	ITGBL1 →	+1.438	+0.520	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,736 associations by consensus.

EFEMP1 vs MGP — BRCA

Explore this scatter interactively →