EFEMP1

Across TCGA cell cohorts, EFEMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,207 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EFEMP1-associated GO terms across cancer lineages are Post-embryonic eye morphogenesis, Positive regulation of intracellular protein transport, and Symbiont entry into host. Each is linked with EFEMP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both EFEMP1-to-partner and partner-to-EFEMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-embryonic eye morphogenesis grouped by EFEMP1-low versus EFEMP1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFEMP1→partner) and Y-score (partner→EFEMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Post-embryonic eye morphogenesis →	+1.501	+4.824	<.001	<.001	3	15
BONE	Positive regulation of intracellular protein transport →	+0.076	+4.461	.006	.003	3	13
BONE	Symbiont entry into host →	+0.094	+3.531	<.001	<.001	3	13
BONE	Symbiont entry into host cell →	+0.094	+3.531	<.001	<.001	3	13
BONE	Viral process →	+0.075	+3.954	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Maintenance of protein location in cell →	+0.139	+5.612	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,207 associations by consensus.

Post-embryonic eye morphogenesis by EFEMP1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →