Across TCGA patient cohorts, EFCAB8 mutation is significantly associated with the RNA expression of many other genes, with 2,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB8-associated genes across cancer lineages are SS18L2P2, OOEPP1, and MIR6769B. Each is linked with EFCAB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB8-to-partner and partner-to-EFCAB8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB8→partner) and Y-score (partner→EFCAB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	SS18L2P2 →	+0.557	+3.584	<.001	.002	3	2
ESCA	OOEPP1 →	+0.321	+3.884	.003	.002	3	2
ESCA	MIR6769B →	+0.276	+3.491	.002	.005	3	2
LIHC	RNU6-1034P →	+0.224	+4.894	<.001	.004	3	2
LIHC	RCC2P8 →	+0.044	+3.868	<.001	.006	3	2
UCEC	CCL5 →	+0.829	+2.016	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,329 associations by consensus.

Exploration

EFCAB8 survival (RNA) · tumor vs normal (RNA) · all EFCAB8 data types