Across TCGA patient cohorts, EFCAB8 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB8-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and C-Raf. Each is linked with EFCAB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB8-to-partner and partner-to-EFCAB8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB8→partner) and Y-score (partner→EFCAB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.528	-1.893	<.001	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.627	+1.415	<.001	.010	3	2
UCEC	C-Raf →	+0.118	+1.678	.007	.021	3	2
UCEC	Cyclin-B1 →	+0.626	+1.893	<.001	<.001	3	2
UCEC	Di-Ras3 →	-0.098	-1.687	.033	.040	3	2
COAD	FASN →	+0.406	+2.330	.021	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration

EFCAB8 survival (RNA) · tumor vs normal (RNA) · all EFCAB8 data types