Across TCGA cell cohorts, EFCAB8 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EFCAB8-associated genes across cancer lineages are FHL5, MS4A6E, and OR11A1. Each is linked with EFCAB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB8-to-partner and partner-to-EFCAB8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB8→partner) and Y-score (partner→EFCAB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FHL5 →	+0.162	+4.415	<.001	.007	3	1
SKIN	MS4A6E →	+0.030	+4.415	.005	.007	3	1
SKIN	OR11A1 →	+0.014	+4.684	<.001	.002	3	1
SKIN	OOSP4B →	+0.066	+5.562	<.001	<.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.031	+4.273	<.001	.006	3	1
LUNG_NSCLC_LUAD	WFDC6 →	+0.050	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

EFCAB8 survival (RNA) · tumor vs normal (RNA) · all EFCAB8 data types