Across TCGA cell cohorts, EFCAB7 mutation is significantly associated with the mutation status of many other genes, with 1,740 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EFCAB7-associated genes across cancer lineages are GREB1, TNPO2, and GBF1. Each is linked with EFCAB7 in more than 3 cancer types. Because this analysis shows association rather than direction, both EFCAB7-to-partner and partner-to-EFCAB7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB7→partner) and Y-score (partner→EFCAB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	GREB1 →	+3.199	+4.633	.003	.003	1	4
BLOOD_Lymphoma	TNPO2 →	+4.169	+5.316	<.001	<.001	1	4
BLOOD_Lymphoma	GBF1 →	+3.584	+4.922	.001	.001	1	4
BLOOD_Leukemia	FBXO11 →	+4.000	+5.050	.008	.008	1	4
BLOOD_Lymphoma	ATP2B1 →	+4.584	+5.554	<.001	<.001	1	4
BLOOD_Leukemia	EPHB1 →	+4.000	+5.050	.008	.008	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,740 associations by consensus.

Exploration

EFCAB7 survival (RNA) · tumor vs normal (RNA) · all EFCAB7 data types