EFCAB13

Across TCGA cell cohorts, EFCAB13 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible EFCAB13-associated genes across cancer lineages are C12orf40, USP17L3, and GALNTL5. Each is linked with EFCAB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB13-to-partner and partner-to-EFCAB13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C12orf40 grouped by EFCAB13-low versus EFCAB13-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB13→partner) and Y-score (partner→EFCAB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	C12orf40 →	+0.024	+4.217	<.001	.005	3	2
URINARY_TRACT	USP17L3 →	+0.019	+5.044	<.001	<.001	3	2
URINARY_TRACT	GALNTL5 →	+0.037	+4.087	<.001	.009	3	1
URINARY_TRACT	IL3 →	+0.020	+4.087	<.001	.009	3	1
URINARY_TRACT	KRTAP19-4 →	+0.145	+4.087	<.001	.009	3	1
URINARY_TRACT	OR2C3 →	+0.022	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

C12orf40 by EFCAB13 expression — URINARY_TRACT

Explore this box plot interactively →