EFCAB13

Across TCGA pan-cancer cohorts, EFCAB13 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated EFCAB13 data layer compared with 4 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EFCAB13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EFCAB13 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

KIRC, ACC, and KIRP are the cancer types where EFCAB13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.530	0.707	.005	52	view →
ACC	DFS	Median	III,IV	0.164	0.478	.006	50	view →
KIRP	DFS	Tertile	All	0.777	0.920	.002	48	view →
LGG	DFS	Median	All	0.656	0.806	<.001	45	view →
COAD	DFS	Median	All	0.727	0.835	<.001	42	view →
SKCM	OS	Median	All	0.401	0.232	<.001	34	view →
UCS	DFS	Tertile	IV	0.975	0.237	.024	30	view →
BLCA	OS	Tertile	IV	0.698	0.443	.007	24	view →
LUAD	OS	Quartile	II,III,IV	0.796	0.559	.006	19	view →
READ	OS	Tertile	II,III,IV	0.880	0.261	.004	18	view →
CESC	OS	Tertile	IV	0.629	0.217	.047	12	view →
BRCA	OS	Median	IV	0.961	0.497	.007	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

EFCAB13–KIRC (DFS)

Open the KIRC breakdown →