EFCAB11

Across TCGA patient cohorts, EFCAB11 mutation is significantly associated with the RNA expression of many other genes, with 2,258 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB11-associated genes across cancer lineages are ZNF519P4, GCATP1, and CASTOR2. Each is linked with EFCAB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB11-to-partner and partner-to-EFCAB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF519P4 grouped by EFCAB11-low versus EFCAB11-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB11→partner) and Y-score (partner→EFCAB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF519P4 →	+0.408	+4.554	<.001	.009	3	2
UCEC	GCATP1 →	+0.497	+3.609	<.001	.001	3	1
UCEC	CASTOR2 →	+0.782	+2.447	<.001	.001	3	1
UCEC	RN7SL248P →	+0.091	+3.815	<.001	<.001	3	1
UCEC	TMEM269 →	+0.205	+3.119	<.001	<.001	3	1
UCEC	LINC02340 →	+0.408	+2.804	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,258 associations by consensus.

ZNF519P4 by EFCAB11 expression — LUAD

Explore this box plot interactively →