EFCAB1

Across TCGA patient cohorts, EFCAB1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,284 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EFCAB1-associated genes across cancer lineages are RSPH4A, CFAP58, and CDHR3. Each is linked with EFCAB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EFCAB1-to-partner and partner-to-EFCAB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EFCAB1 versus RSPH4A in UCEC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB1→partner) and Y-score (partner→EFCAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RSPH4A →	+4.160	+2.330	.003	.004	3	3
UCEC	CFAP58 →	+2.857	+2.152	<.001	.002	3	3
UCEC	CDHR3 →	+4.085	+2.152	.002	.002	3	3
UCEC	CNGA4 →	+4.299	+2.596	<.001	.002	3	3
UCEC	RGS22 →	+2.050	+2.012	.009	.005	3	3
UCEC	STOML3 →	+4.846	+2.596	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,284 associations by consensus.

EFCAB1 vs RSPH4A — UCEC

Explore this scatter interactively →