EFCAB1

Across TCGA patient cohorts, EFCAB1 mutation is significantly associated with the RNA expression of many other genes, with 782 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB1-associated genes across cancer lineages are RNA5SP394, PAICSP6, and MIR3928. Each is linked with EFCAB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EFCAB1-to-partner and partner-to-EFCAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP394 grouped by EFCAB1-low versus EFCAB1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB1→partner) and Y-score (partner→EFCAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP394 →	+0.481	+5.836	<.001	<.001	3	2
LUSC	PAICSP6 →	+0.045	+5.038	<.001	.009	3	2
LUAD	MIR3928 →	+1.148	+5.285	<.001	.001	3	2
LUAD	MIR6803 →	+0.423	+4.798	<.001	.006	3	2
UCEC	BUB3 →	+0.772	+3.534	<.001	.002	3	2
UCEC	SETD9 →	+0.544	+3.338	.008	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 782 associations by consensus.

RNA5SP394 by EFCAB1 expression — BLCA

Explore this box plot interactively →