EFCAB1

Across TCGA cell cohorts, EFCAB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,167 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible EFCAB1-associated GO terms across cancer lineages are Regulation of intrinsic apoptotic signaling pathway, Maintenance of protein localization in organelle, and Maintenance of location in cell. Each is linked with EFCAB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EFCAB1-to-partner and partner-to-EFCAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intrinsic apoptotic signaling pathway grouped by EFCAB1-low versus EFCAB1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB1→partner) and Y-score (partner→EFCAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of intrinsic apoptotic signaling pathway →	+0.061	+1.088	.002	.006	2	7
LIVER	Maintenance of protein localization in organelle →	+0.141	+0.567	<.001	.003	3	6
URINARY_TRACT	Maintenance of location in cell →	+0.057	+1.141	.001	.001	3	6
OESOPHAGUS	Glial cell migration →	+0.154	+1.320	<.001	.002	3	5
OESOPHAGUS	Purine ribonucleoside triphosphate metabolic process →	+0.135	+1.070	<.001	.003	3	5
PANCREAS	Positive regulation of fibroblast proliferation →	+0.117	+1.238	.004	.006	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,167 associations by consensus.

Regulation of intrinsic apoptotic signaling pathway by EFCAB1 expression — URINARY_TRACT

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