EEPD1

Across TCGA patient cohorts, EEPD1 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EEPD1-associated genes across cancer lineages are mTOR_pS2448, c-Kit, and Acetyl-a-Tubulin-Lys40. Each is linked with EEPD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EEPD1-to-partner and partner-to-EEPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR_pS2448 grouped by EEPD1-low versus EEPD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EEPD1→partner) and Y-score (partner→EEPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.148	-3.156	.011	.018	3	4
UCEC	c-Kit →	-0.195	-2.000	.033	.010	3	3
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.495	+1.594	.013	.042	3	2
UCEC	INPP4B →	-0.297	-2.321	.019	.033	3	2
UCEC	ATM →	-0.572	-2.308	.001	.033	3	2
STAD	ER-alpha_pS118 →	+0.144	+2.838	.002	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

mTOR_pS2448 by EEPD1 expression — UCEC

Explore this box plot interactively →