EEPD1

Across TCGA pan-cancer cohorts, EEPD1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of EEPD1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where EEPD1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EEPD1 is over-expressed in tumor, although a few such as BLCA and BRCA show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where EEPD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EEPD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.645	<.001	11	view →
COAD	All	IV	+1.578	<.001	10	view →
LIHC	All	III,IV	+1.136	<.001	9	view →
KIRP	All	All	+0.604	<.001	9	view →
BLCA	Male	All	−1.479	<.001	8	view →
BRCA	All	II,III,IV	−1.580	<.001	6	view →
KICH	Female	All	+1.270	<.001	4	view →
UCEC	All	IV	+0.780	.025	4	view →
THCA	Male	III,IV	−0.601	.008	4	view →
STAD	Male	II,III,IV	+0.784	.004	3	view →
CHOL	Male	All	+1.700	<.001	2	view →
STAD	Female	III,IV	−0.949	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

EEPD1–KIRC

Open the KIRC breakdown →